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24. Kongress der DGII 2010
Abstracts DGII 2010
V.
Wissenschaftliche
Sitzung: Allgemeines/Varia
R34
The Role of the Soemmerring’s Ring in the
Pathogenesis of Post-Capsule Opacification
and other Post-Surgical Opacifications
Apple DJ1, Borkenstein AF1, Kleinmann G1, Zuagg B1,
Auffarth G2
1 David J. Apple Laboratories for Ophthalmic Devices Research, Sullivan’s Island (USA),
2 Universitäts-Augenklinik Heidelberg
Purpose:
In this study we test the hypothesis that the
Soemmerring’s Ring (SR)is the structure of origin of multiple conditions
ranging from simple PCO to capsular phimosis, with many in between.
Methods:
We examined the anterior segment structures of eyes that
have had previous cataract surgery with special reference to a
tracing of cells from the region of the peripheral lens to the point
within the eye where they settle.
Results:
Examination of the capsular
bags of 500 eyes revealed 3 levels of intracapsular LEC activity after
ECCE.
Conclusions:
The degree of cell proliferation in the capsular
bags was higher than expected. (LECs and SR). To date there are no
surgical means to remove 100% of LECs! A Soemmerring’s Ring, the
precursor of PCO and all other forms of post-surgical fibrosis of
phakic and specialized IOLs occurs in 100% of cases after 5 to 7 years.
All IOL models are susceptible to a breakout of cells from the
Soemmerring’s Ring after ca. 5 – 7 years. Up to 50% of cases have this
breakout.
Erschienen in:
Klin Monatsbl Augenheilkd 2010; 227: Suppl. 1, S1–S24
Georg Thieme Verlag KG Stuttgart · New York · ISSN 1431-634X |